Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 8/20 | 0.85 |
| ▸ | MERTK | Q12866 | 13/20 | 0.74 |
| ▸ | AXL | P30530 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19398147 | 0.92 | TYRO3 (1.00) | TYRO3MERTKAXL | |
| Maleic Acid SCHEMBL29526181 | 0.89 | TYRO3 (0.93) | TYRO3MERTKAXL | |
| SCHEMBL19398176 | 0.85 | MERTK (1.00) | TYRO3MERTKAXL | |
| SCHEMBL23965835 | 0.85 | TYRO3 (0.87) | TYRO3MERTK | |
| SCHEMBL19398177 | 0.84 | MERTK (1.00) | TYRO3MERTKAXL | |
| SCHEMBL30367450 | 0.84 | TYRO3 (0.81) | TYRO3MERTKAXL | |
| SCHEMBL19398128 | 0.84 | TYRO3 (1.00) | TYRO3MERTKAXL | |
| SCHEMBL19398182 | 0.83 | MERTK (1.00) | TYRO3MERTKAXL | |
| SCHEMBL19398178 | 0.83 | MERTK (0.83) | TYRO3MERTKAXL | |
| SCHEMBL20869661 | 0.82 | TYRO3 (0.70) | TYRO3MERTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988552-A1 | SALTS OF PYRROLOTRIAZINE DERIVATIVES USEFUL AS TAM INHIBITORS | Incyte Corporation (US) | 2022-04-27 | — | — | EP | disclosed |