Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | ACHE | P22303 | 5/20 | 0.54 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.53 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.53 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.53 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948255 | 1.00 | LMNA (1.00) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL29609278 | 1.00 | LMNA (1.00) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL5983791 | 1.00 | LMNA (1.00) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL3770300 | 1.00 | LMNA (1.00) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL13012214 | 1.00 | LMNA (1.00) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL13062149 | 1.00 | LMNA (1.00) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL6884789 | 1.00 | LMNA (1.00) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL21798516 | 1.00 | LMNA (1.00) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL22826797 | 1.00 | LMNA (1.00) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL5410879 | 1.00 | LMNA (1.00) | LMNATP53ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988100-A1 | ADENOSINE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR STEREOISOMERIDE THEREOF, AND USE | Academy Of Military Medical Sciences (CN) | 2022-04-27 | — | — | EP | disclosed |
| EP-3988559-A1 | 2-BENZYLIDENE HYDRAZINOADENOSINE COMPOUNDS HAVING A2A ADENOSINE RECEPTOR AGNOSTIC ACTIVITY | Academy Of Military Medical Sciences (CN) | 2022-04-27 | — | — | EP | disclosed |