SCHEMBL2437216

SCHEMBL2437216

CCCCCCCCCCCCCC(=O)C(=O)C=CC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.58
CES1 P23141 4/20 0.58
GPR84 Q9NQS5 6/20 0.50
PPARG P37231 6/20 0.50
PPARD Q03181 6/20 0.50
PPARA Q07869 6/20 0.50
HDAC11 Q96DB2 5/20 0.50
TSHR P16473 4/20 0.50
ALDH1A1 P00352 2/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
FABP4 P15090 2/20 0.50
PTPN1 P18031 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50
MEN1 O00255 1/20 0.50
ESR1 P03372 1/20 0.50
ALOX15 P16050 1/20 0.50
PDE4A P27815 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Podoscyphic Acid SCHEMBL2437877 1.00 CES2 (0.58) CES2CES1GPR84PPARGPPARD
SCHEMBL547458 1.00 CES2 (0.58) CES2CES1GPR84PPARGPPARD
SCHEMBL547457 1.00 CES2 (0.58) CES2CES1GPR84PPARGPPARD
SCHEMBL7952574 0.89 CES2 (0.54) CES2CES1GPR84PPARGPPARD
SCHEMBL26463501 0.84 CES1 (0.58) CES2CES1GPR84PPARGPPARD
SCHEMBL4915612 0.83 CES2 (0.50) CES2CES1TSHRHCAR2
SCHEMBL4915610 0.83 CES2 (0.50) CES2CES1TSHRHCAR2
Nonane SCHEMBL8691965 0.82 HCAR2 (0.65) GPR84PPARGPPARDPPARAHDAC11
Fumaric Acid SCHEMBL3414623 0.82 HCAR2 (0.65) GPR84PPARGPPARDPPARAHDAC11
Octane SCHEMBL6872114 0.82 HCAR2 (0.65) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1698458-B1 LAMINATE NIPPON SYNTHETIC CHEM IND (JP) 2011-09-14 EP disclosed
US-20090162305-A1 FORMULATIONS OF LOW OIL CONTENT COMPRISING DIPHENYLMETHANE DERIVATIVES SYMRISE GMBH & CO. KG (DE) 2009-06-25 US disclosed
EP-1973519-A1 FORMULATIONS OF LOW OIL CONTENT COMPRISING DIPHENYLMETHANE DERIVATIVES Symrise GmbH & Co. KG (DE) 2008-10-01 EP disclosed
WO-2007077260-A9 FORMULATIONS OF LOW OIL CONTENT COMPRISING DIPHENYLMETHANE DERIVATIVES SYMRISE GMBH & CO KG (DE) 2007-09-13 WO disclosed
WO-2007077260-A1 FORMULATIONS OF LOW OIL CONTENT COMPRISING DIPHENYLMETHANE DERIVATIVES SYMRISE GMBH & CO. KG (DE) 2007-07-12 WO disclosed
US-20070148481-A1 Laminated article NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD., THE (JP) 2007-06-28 US disclosed
EP-1698458-A1 LAMINATE The Nippon Synthetic Chemical Industry Co., Ltd. (JP) 2006-09-06 EP disclosed
US-6352785-B1 FOOD WRAP SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2002-03-05 US disclosed
EP-0403109-B1 Resin composition and shaped article thereof MITSUBISHI CHEM CORP (JP) 1995-11-02 EP disclosed
US-5219929-A High strength, toughness, oxygen barriers MITSUBISHI KASEI POLYTEC COMPANY (JP) 1993-06-15 US disclosed
EP-0403109-A2 Resin composition and shaped article thereof Mitsubishi Chemical Corporation (JP) 1990-12-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090162305-A1 FORMULATIONS OF LOW OIL CONTENT COMPRISING DIPHENYLMETHANE DERIVATIVES TYR, CYP51A1, DDT CES2 2064/4885CES1 156/4885GPR84 1330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.