Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6366994 | 0.84 | CYP1A2 (0.57) | CYP1A2CYP2A6ALDH1A1HSD17B10BACE1 | |
| SCHEMBL12109427 | 0.81 | UGT2B7 (0.55) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL9319123 | 0.78 | CYP1A2 (0.55) | CYP1A2CYP2A6ALDH1A1HSD17B10BACE1 | |
| SCHEMBL16646888 | 0.78 | CYP1A2 (0.55) | CYP1A2CYP2A6ALDH1A1HSD17B10BACE1 | |
| SCHEMBL23226920 | 0.78 | CYP1A2 (0.50) | CYP1A2CYP2A6ALDH1A1HSD17B10BACE1 | |
| SCHEMBL11741422 | 0.77 | CYP1A2 (0.48) | CYP1A2CYP2A6ALDH1A1HSD17B10BACE1 | |
| SCHEMBL1000819 | 0.72 | UGT2B7 (0.49) | CYP1A2AKR1B1UGT2B7TSHRSLC6A2 | |
| SCHEMBL25434816 | 0.71 | UGT2B7 (0.63) | CYP1A2UGT2B7TSHRSLC6A2SLC6A4 | |
| SCHEMBL24200933 | 0.71 | HTR2A (0.45) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL14019306 | 0.71 | UGT2B7 (0.63) | CYP1A2UGT2B7TSHRSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087475-A1 | REVERSE TRANSCRIPTION OF POLYNUCLEOTIDES COMPRISING UNNATURAL NUCLEOTIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-04-28 | — | — | WO | disclosed |