SCHEMBL6366994

SCHEMBL6366994

Cc1cc(C(C)C)cc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.57
CYP2A6 P11509 4/20 0.57
ALDH1A1 P00352 4/20 0.46
UGT2B7 P16662 1/20 0.44
HSD17B10 Q99714 2/20 0.41
HPGD P15428 1/20 0.41
AKR1B1 P15121 1/20 0.39
KIF11 P52732 1/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 2/20 0.39
HIF1A Q16665 1/20 0.38
CYP1B1 Q16678 1/20 0.38
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
BACE1 P56817 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24372234 0.84 CYP1A2 (0.53) CYP1A2CYP2A6ALDH1A1UGT2B7HSD17B10
SCHEMBL12109427 0.84 UGT2B7 (0.55) CYP1A2CYP2A6ALDH1A1UGT2B7HSD17B10
SCHEMBL9319123 0.82 CYP1A2 (0.55) CYP1A2CYP2A6ALDH1A1UGT2B7HSD17B10
SCHEMBL16646888 0.82 CYP1A2 (0.55) CYP1A2CYP2A6ALDH1A1UGT2B7HSD17B10
SCHEMBL598273 0.81 HPRT1 (0.45) CYP1A2CYP2A6ALDH1A1UGT2B7HSD17B10
SCHEMBL23226920 0.81 CYP1A2 (0.50) CYP1A2CYP2A6ALDH1A1UGT2B7HSD17B10
SCHEMBL11741422 0.80 CYP1A2 (0.48) CYP1A2CYP2A6ALDH1A1UGT2B7HSD17B10
SCHEMBL2173494 0.79 UGT2B7 (0.44) CYP1A2CYP2A6ALDH1A1UGT2B7HSD17B10
SCHEMBL23518912 0.78 UGT2B7 (0.42) CYP1A2CYP2A6ALDH1A1UGT2B7HSD17B10
SCHEMBL24406020 0.78 UGT2B7 (0.42) CYP1A2CYP2A6ALDH1A1UGT2B7HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100439315-C Process for producing 1,3-naphthalenedicarboxylic acid MITSUBISHI GAS CHEMICAL CO (JP) 2008-12-03 CN disclosed
CN-1680263-A Process for producing 1,3-naphthalenedicarboxylic acid MITSUBISHI GAS CHEMICAL CO (JP) 2005-10-12 CN disclosed
US-20050187403-A1 Process for producing 1,3-naphthalenedicarboxylic acid MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-08-25 US disclosed