Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24357923 | 0.81 | DPP4 (0.30) | DPP4DPP7NAMPT | |
| SCHEMBL490276 | 0.69 | — | — | |
| SCHEMBL18381572 | 0.69 | ALDH1A1 (0.38) | — | |
| SCHEMBL13746132 | 0.66 | DPP4 (0.45) | DPP4DPP7NAMPT | |
| SCHEMBL22436717 | 0.65 | — | — | |
| SCHEMBL13659925 | 0.62 | — | — | |
| SCHEMBL23158239 | 0.60 | — | — | |
| SCHEMBL28149214 | 0.60 | DPP4 (0.47) | DPP4DPP7NAMPT | |
| SCHEMBL19722711 | 0.60 | EPHX2 (0.38) | DPP4DPP7 | |
| SCHEMBL286213 | 0.59 | HSD17B10 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087371-A1 | NOVEL BICYCLIC COMPOUNDS | SPECTRUM PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |