Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24372437 | 0.99 | HSD11B1 (0.57) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24372369 | 0.84 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24372411 | 0.84 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31042808 | 0.83 | HSD11B1 (0.53) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24372403 | 0.83 | HSD11B1 (0.53) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24372376 | 0.83 | HSD11B1 (0.53) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5094217 | 0.82 | HSD11B1 (0.61) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL17790202 | 0.78 | HPGD (0.60) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL5091254 | 0.78 | CHRM3 (0.54) | HSD11B1DPP7EP300 | |
| SCHEMBL17790256 | 0.76 | HPGD (0.57) | MEN1KMT2AALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988090-A1 | P62 LIGAND COMPOUND AND ER-PHAGY-PROMOTING USE THEREOF | Protech Inc. (KR) | 2022-04-27 | — | — | EP | disclosed |