Sugi Predict

Sugi Predict / Compounds / SCHEMBL24372686

SCHEMBL24372686

SCHEMBL24372686

c1ccc(-c2nc(-c3ccc(-c4cccc5oc6ccccc6c45)cc3)nc(-n3c4ccccc4c4ccccc43)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 1/20 0.39
▸ MAPT P10636 5/20 0.36
▸ KDM4E B2RXH2 4/20 0.35
▸ ALDH1A1 P00352 4/20 0.35
▸ TSHR P16473 3/20 0.35
▸ MAPK1 P28482 2/20 0.35
▸ HSD17B10 Q99714 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ ATM Q13315 2/20 0.35
▸ TP53 P04637 1/20 0.35
▸ NFKB1 P19838 1/20 0.35
▸ NFKB2 Q00653 1/20 0.35
▸ RELA Q04206 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ LMNA P02545 2/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.34
▸ MEN1 O00255 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25661308 0.95 BACE1 (0.40) BACE1MAPTKDM4EALDH1A1TSHR
SCHEMBL22737566 0.94 BACE1 (0.36) BACE1MAPTKDM4EALDH1A1TSHR
SCHEMBL31744516 0.94 BACE1 (0.35) BACE1MAPTKDM4EALDH1A1TSHR
SCHEMBL24217186 0.94 BACE1 (0.35) BACE1MAPTKDM4EALDH1A1TSHR
SCHEMBL21583573 0.94 BACE1 (0.35) BACE1MAPTKDM4EALDH1A1TSHR
SCHEMBL24855824 0.94 MAPT (0.35) BACE1MAPTKDM4EALDH1A1TSHR
SCHEMBL25661361 0.94 BACE1 (0.39) BACE1MAPTKDM4EALDH1A1TSHR
SCHEMBL24151977 0.94 TSHR (0.36) BACE1MAPTKDM4EALDH1A1TSHR
SCHEMBL22738156 0.93 MAPT (0.36) BACE1MAPTKDM4EALDH1A1TSHR
SCHEMBL22737810 0.93 HCRTR1 (0.36) BACE1MAPTKDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-09-07 — — US disclosed
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-09-07 — — US disclosed
US-20220131083-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131083-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, TERT, LIMS1 BACE1 1511/4885MAPT 2033/4885KDM4E 3373/4885
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND OR10J3, ICOSLG, L1CAM BACE1 3221/4885MAPT 1652/4885KDM4E 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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