Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17173286 | 0.79 | TSHR (0.35) | TSHRTDP1 | |
| SCHEMBL13310541 | 0.72 | — | — | |
| SCHEMBL14459671 | 0.67 | PIK3CD (0.37) | ALDH1A1TSHRTDP1 | |
| SCHEMBL24465083 | 0.67 | — | — | |
| SCHEMBL22778936 | 0.64 | — | — | |
| SCHEMBL17773061 | 0.64 | HMGCR (0.41) | ALDH1A1TSHRTDP1 | |
| SCHEMBL25131085 | 0.64 | — | — | |
| SCHEMBL10829546 | 0.64 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL812869 | 0.62 | TSHR (0.40) | ALDH1A1TSHRTDP1 | |
| SCHEMBL19251038 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087216-A1 | DOUBLE DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |