Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12316359 | 0.96 | IDO1 (0.52) | IDO1TAAR1AGXTABCC4LMNA | |
| SCHEMBL438984 | 0.89 | IDO1 (0.59) | IDO1TSHRALDH1A1KDM4ECYP1A2 | |
| SCHEMBL436644 | 0.89 | IDO1 (0.59) | IDO1TSHRALDH1A1KDM4ECYP1A2 | |
| SCHEMBL14705252 | 0.87 | IDO1 (0.68) | IDO1TAAR1AGXTABCC4LMNA | |
| SCHEMBL1411374 | 0.87 | IDO1 (0.68) | IDO1TAAR1AGXTABCC4LMNA | |
| SCHEMBL12316354 | 0.84 | TAAR1 (0.47) | IDO1TAAR1AGXTABCC4LMNA | |
| SCHEMBL13884024 | 0.83 | TAAR1 (0.48) | IDO1TAAR1AGXTABCC4LMNA | |
| SCHEMBL18288710 | 0.82 | ALDH1A1 (0.56) | TAAR1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL18288714 | 0.82 | ALDH1A1 (0.56) | TAAR1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL15945883 | 0.82 | ALDH1A1 (0.56) | TAAR1ALDH1A1KDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | L1CAM, EPCAM, SELPLG | IDO1 3158/4885TAAR1 1558/4885AGXT 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.