⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24373088 | 1.00 | — | — | |
| SCHEMBL24372980 | 0.74 | — | — | |
| SCHEMBL24372981 | 0.74 | — | — | |
| SCHEMBL25736980 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL35210775 | 0.70 | — | — | |
| SCHEMBL6129777 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL25228946 | 0.70 | — | — | |
| SCHEMBL35210601 | 0.68 | — | — | |
| SCHEMBL17528895 | 0.68 | — | — | |
| SCHEMBL16914406 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022083569-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-04-28 | — | — | WO | disclosed |