SCHEMBL2437486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2441282	0.82	EGLN1 (0.69)	EGLN1RAB9ASMN1; SMN2ALDH1A1NPSR1
	SCHEMBL13818070	0.81	ALDH1A1 (0.64)	KDM5AHIF1ARAB9ASMN1; SMN2ALDH1A1
	SCHEMBL3629411	0.81	EGLN1 (0.43)	EGLN1HIF1ARAB9ASMN1; SMN2ALDH1A1
	SCHEMBL2578927	0.81	HIF1A (0.67)	EGLN1HIF1ARAB9ANPC1MEN1
	SCHEMBL12291923	0.79	EGLN1 (0.76)	EGLN1HIF1ARAB9AALDH1A1NPC1
	SCHEMBL2441228	0.78	EGLN1 (0.58)	EGLN1HIF1ARAB9ASMN1; SMN2ALDH1A1
	SCHEMBL2435683	0.78	EGLN1 (1.00)	EGLN1HIF1ARAB9AALDH1A1NPC1
	SCHEMBL2438424	0.78	EGLN1 (0.74)	EGLN1HIF1ARAB9AALDH1A1NPC1
	SCHEMBL2441366	0.77	EGLN1 (0.56)	EGLN1HIF1ARAB9AALDH1A1NPSR1
	SCHEMBL2435696	0.76	EGLN1 (0.71)	EGLN1HIF1ARAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.