Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | RXRA | P19793 | 2/20 | 0.70 |
| ▸ | RXRB | P28702 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | XBP1 | P17861 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | MITF | O75030 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | RXRG | P48443 | 1/20 | 0.63 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9647665 | 0.98 | MRGPRX4 (0.71) | MRGPRX4HPGDRXRARXRBNPC1 | |
| SCHEMBL8756076 | 0.89 | MRGPRX4 (0.61) | MRGPRX4HPGDRXRARXRBNPC1 | |
| SCHEMBL698500 | 0.88 | MRGPRX4 (0.80) | MRGPRX4HPGDRXRARXRBNPC1 | |
| SCHEMBL8768763 | 0.88 | MRGPRX4 (0.78) | MRGPRX4HPGDRXRARXRBNPC1 | |
| SCHEMBL38658646 | 0.88 | MRGPRX4 (0.59) | MRGPRX4HPGDRXRARXRBNPC1 | |
| SCHEMBL9659745 | 0.88 | MRGPRX4 (0.59) | MRGPRX4HPGDRXRARXRBNPC1 | |
| SCHEMBL1934576 | 0.88 | HPGD (0.70) | MRGPRX4HPGDRXRARXRBNPC1 | |
| SCHEMBL16584995 | 0.87 | MRGPRX4 (0.58) | MRGPRX4HPGDRXRARXRBNPC1 | |
| SCHEMBL8768764 | 0.87 | MRGPRX4 (0.58) | MRGPRX4HPGDRXRARXRBNPC1 | |
| SCHEMBL2705229 | 0.86 | MRGPRX4 (0.65) | MRGPRX4HPGDRXRARXRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836157-A | Oxadiazole derivative and preparation method and application thereof | 星希尔生物科技(上海)有限公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2023179366-A1 | OXADIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 星希尔生物科技(上海)有限公司 | 2023-09-28 | — | — | WO | disclosed |
| US-9994558-B2 | Multicyclic compounds and methods of using same | Karyopharm Therapeutics Inc. (US) | 2018-06-12 | — | — | US | disclosed |
| US-9994558-B2 | Multicyclic compounds and methods of using same | Karyopharm Therapeutics Inc. (US) | 2018-06-12 | — | — | US | disclosed |
| US-9994558-B2 | Multicyclic compounds and methods of using same | Karyopharm Therapeutics Inc. (US) | 2018-06-12 | — | — | US | disclosed |
| CN-103059036-B | Polymerizable chiral compound | DIC株式会社 | 2017-06-06 | — | — | CN | disclosed |
| US-20170096417-A1 | Multicyclic Compounds And Methods Of Using Same | Karyopharm Therapeutics Inc. (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170096417-A1 | Multicyclic Compounds And Methods Of Using Same | Karyopharm Therapeutics Inc. (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170096417-A1 | Multicyclic Compounds And Methods Of Using Same | Karyopharm Therapeutics Inc. (US) | 2017-04-06 | — | — | US | disclosed |
| WO-2015042414-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF USING SAME | Karyopharm Therapeutics Inc. (US) | 2015-03-26 | — | — | WO | disclosed |
| US-5677112-A | USING AN ANTHRACENE COMPOUND | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0635480-B1 | Anthracene derivatives | WAKO PURE CHEM IND LTD (JP) | 1997-03-19 | — | — | EP | disclosed |
| US-5576359-A | ANTHRACENE DERIVATIVE, SOLVENT, COMPOUND CONTAINING GLYCIDYL GROUPS | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0636941-B1 | Deep ultraviolet absorbent and its use in pattern formation | WAKO PURE CHEM IND LTD (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5498748-A | PHENOLIC CROSSLINKER FOR A POLYGLYCIDYL METHACRYLATE TO FORM A MATERIAL USED AS AN ANTIREFLECTION COATING FOR DEEP UV LIGHT SUCH AS KRF EXIMER LASERS IN SEMICONDUCTOR PHOTORESISTS | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0636941-A1 | Deep ultraviolet absorbent and its use in pattern formation | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0635480-A1 | Anthracene derivatives | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1995-01-25 | — | — | EP | disclosed |
| EP-0321984-B1 | MESOMORPHIC COMPOUND HAVING BETA-HYDROXYCARBOXYL GROUP AS CHIRAL SOURCE AND LIQUID CRYSTAL COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |
| US-4925591-A | FERROELECTRIC | MITSUBISHI RAYON CO., LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0321984-A1 | Mesomorphic compound having beta-hydroxycarboxyl group as chiral source and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1989-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170096417-A1 | Multicyclic Compounds And Methods Of Using Same | PAK4, PAK5, PAK1 | MRGPRX4 1667/4885HPGD 2381/4885RXRA 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.