SCHEMBL38658646

SCHEMBL38658646

O=C(O)C(=O)c1ccc(OCc2ccccc2)c(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 8/20 0.59
HPGD P15428 3/20 0.58
RXRA P19793 2/20 0.58
RXRB P28702 2/20 0.58
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
NFKB1 P19838 2/20 0.55
NFKB2 Q00653 2/20 0.55
RELA Q04206 2/20 0.55
TP53 P04637 2/20 0.55
XBP1 P17861 2/20 0.55
MEN1 O00255 1/20 0.55
MITF O75030 1/20 0.55
KMT2A Q03164 1/20 0.55
RXRG P48443 1/20 0.53
MAPT P10636 1/20 0.53
HTT P42858 1/20 0.53
HSD17B10 Q99714 1/20 0.53
PTPRC P08575 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9659745 1.00 MRGPRX4 (0.59) MRGPRX4HPGDRXRARXRBNPC1
SCHEMBL243754 0.88 MRGPRX4 (0.73) MRGPRX4HPGDRXRARXRBNPC1
Hydrochloric Acid SCHEMBL9647665 0.87 MRGPRX4 (0.71) MRGPRX4HPGDRXRARXRBNPC1
SCHEMBL8756076 0.87 MRGPRX4 (0.61) MRGPRX4HPGDRXRARXRBNPC1
SCHEMBL8768763 0.85 MRGPRX4 (0.78) MRGPRX4HPGDRXRARXRBNPC1
SCHEMBL16584995 0.84 MRGPRX4 (0.58) MRGPRX4HPGDRXRARXRBNPC1
SCHEMBL8768764 0.84 MRGPRX4 (0.58) MRGPRX4HPGDRXRARXRBNPC1
SCHEMBL5468617 0.83 MRGPRX4 (0.57) MRGPRX4HPGDRXRARXRBNPC1
SCHEMBL3231604 0.83 MRGPRX4 (0.63) MRGPRX4HPGDRXRARXRBNPC1
SCHEMBL11740327 0.83 HDAC6 (0.71) MRGPRX4HPGDRXRARXRBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098548-A1 PROTEIN DEGRADATION AGENT, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF, AND METHOD 四川科伦博泰生物医药股份有限公司 2026-05-15 WO disclosed