SCHEMBL24375701

SCHEMBL24375701

C=C(C)C(=O)Oc1ccc(OC(C)(C)CC)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.39
KMT2A Q03164 2/20 0.36
ATM Q13315 1/20 0.36
EPHX2 P34913 1/20 0.33
PPARD Q03181 2/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
FAAH O00519 2/20 0.32
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
PDE2A O00408 1/20 0.31
FFAR1 O14842 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24375704 0.87 ELANE (0.42) ELANEKMT2AATMEPHX2PPARD
SCHEMBL9999348 0.81 ELANE (0.50) ELANEKMT2AATMPPARGPPARA
SCHEMBL11230872 0.80 ELANE (0.43) ELANEKMT2AATMPPARDPPARG
SCHEMBL26334784 0.80 KMT2A (0.38) KMT2AFAAHMAPT
SCHEMBL29019507 0.79 LMNA (0.49) ELANEKMT2AATMMAPT
SCHEMBL19998062 0.76 ELANE (0.43) ELANEKMT2AATMPPARDPPARG
SCHEMBL12636054 0.76 ELANE (0.50) ELANEKMT2AATMPOLBMAPT
SCHEMBL20862847 0.75 ELANE (0.46) ELANEKMT2AATMPOLBMAPT
SCHEMBL9607783 0.74 ELANE (0.49) ELANEKMT2AATMPOLBMAPT
SCHEMBL1098577 0.74 ELANE (0.40) ELANEKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220128904-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-04-28 US disclosed