Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.68 |
| ▸ | CASP2 | P42575 | 1/20 | 0.55 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.52 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5438759 | 1.00 | EPHX1 (0.68) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL17694454 | 1.00 | EPHX1 (0.68) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL21738174 | 1.00 | EPHX1 (0.68) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL13701713 | 1.00 | EPHX1 (0.68) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL5439873 | 1.00 | EPHX1 (0.68) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL19478069 | 1.00 | EPHX1 (0.68) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL26312872 | 1.00 | EPHX1 (0.68) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL6840451 | 0.98 | EPHX1 (0.64) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| Sulfuric Acid SCHEMBL27634420 | 0.94 | EPHX1 (0.61) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| Sulfuric Acid SCHEMBL27634416 | 0.94 | EPHX1 (0.61) | EPHX1CASP2ZDHHC20ZDHHC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694505-B1 | HSP90 INHIBITORS | SLOAN KETTERING INST CANCER RES (US) | 2022-04-27 | — | — | EP | disclosed |