Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.64 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17694454 | 0.98 | EPHX1 (0.68) | EPHX1CASP2POLBZDHHC20ZDHHC2 | |
| SCHEMBL5438759 | 0.98 | EPHX1 (0.68) | EPHX1CASP2POLBZDHHC20ZDHHC2 | |
| SCHEMBL5439873 | 0.98 | EPHX1 (0.68) | EPHX1CASP2POLBZDHHC20ZDHHC2 | |
| SCHEMBL26312872 | 0.98 | EPHX1 (0.68) | EPHX1CASP2POLBZDHHC20ZDHHC2 | |
| SCHEMBL13701713 | 0.98 | EPHX1 (0.68) | EPHX1CASP2POLBZDHHC20ZDHHC2 | |
| SCHEMBL24376776 | 0.98 | EPHX1 (0.68) | EPHX1CASP2POLBZDHHC20ZDHHC2 | |
| SCHEMBL21738174 | 0.98 | EPHX1 (0.68) | EPHX1CASP2POLBZDHHC20ZDHHC2 | |
| SCHEMBL19478069 | 0.98 | EPHX1 (0.68) | EPHX1CASP2POLBZDHHC20ZDHHC2 | |
| SCHEMBL2736685 | 0.93 | EPHX1 (0.55) | EPHX1POLBALDH1A1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL27634420 | 0.92 | EPHX1 (0.61) | EPHX1CASP2POLBZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226026-A1 | BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ARES CAPITAL CORPORATION, AS AGENT | 2024-07-11 | — | — | US | disclosed |
| US-20230212549-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2023-07-06 | — | — | US | disclosed |
| US-20230212549-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2023-07-06 | — | — | US | disclosed |
| US-20220160887-A1 | PROGRAMMABLE POLYMERIC DRUGS | Sony Group Corporation (JP) | 2022-05-26 | — | — | US | disclosed |
| US-10989715-B2 | Ultra bright dimeric or polymeric dyes with spacing linker groups | SONY CORPORATION (JP) | 2021-04-27 | — | — | US | disclosed |
| US-20210101878-A1 | Cannabinergic Compounds And Uses Thereof | NORTHEASTERN UNIVERSITY | 2021-04-08 | — | — | US | disclosed |
| US-10882838-B2 | Cannabinergic compounds and uses thereof | NORTHEASTERN UNIVERSITY (US) | 2021-01-05 | — | — | US | disclosed |
| US-20200284798-A1 | ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS | SONY CORPORATION (JP) | 2020-09-10 | — | — | US | disclosed |
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
| US-10550073-B2 | Benzamide derivative | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
| US-20160108016-A1 | Novel Cannabinergic Compounds and Uses Thereof | NORTHEASTERN UNIVERSITY (US) | 2016-04-21 | — | — | US | disclosed |
| US-20160108016-A1 | Novel Cannabinergic Compounds and Uses Thereof | NORTHEASTERN UNIVERSITY (US) | 2016-04-21 | — | — | US | disclosed |
| US-9273058-B2 | Substituted pyrazolo-piperazines as casein kinase 1 δ/ε inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150133428-A1 | NOVEL SUBSTITUTED PYRAZOLO-PIPERAZINES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2015-05-14 | — | — | US | disclosed |
| US-8653141-B2 | HIV protease inhibiting compounds | ABBVIE INC. (US) | 2014-02-18 | — | — | US | disclosed |
| US-8623857-B2 | N-phenyl imidazole carboxamide inhibitors of 3-phosphoinositide-dependent protein kinase-1 | MERCK SHARP & DOHME CORP. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20130079326-A1 | N-PHENYL IMIDAZOLE CARBOXAMIDE INHIBITORS OF 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 | MERCK SHARP & DOHME CORP. | 2013-03-28 | — | — | US | disclosed |
| US-20130023463-A1 | HIV PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | US | disclosed |
| US-8193227-B2 | HIV protease inhibiting compounds | ABBOTT LABORATORIES (US) | 2012-06-05 | — | — | US | disclosed |
| US-20110003827-A1 | HIV protease inhibiting compounds | ABBVIE INC. | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200284798-A1 | ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS | IK, MTCL3, RRM1 | EPHX1 4538/4885CASP2 4197/4885POLB 3224/4885 |
| US-20110003827-A1 | HIV protease inhibiting compounds | SERPINB1, HPN, DNPEP | EPHX1 2053/4885CASP2 466/4885POLB 733/4885 |
| US-20230212549-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | FIBP, FN1, TPX2 | EPHX1 3676/4885CASP2 1966/4885POLB 4824/4885 |
| US-20220160887-A1 | PROGRAMMABLE POLYMERIC DRUGS | CHRM1, NCL, PBRM1 | EPHX1 4563/4885CASP2 4337/4885POLB 887/4885 |
| US-20130023463-A1 | HIV PROTEASE INHIBITING COMPOUNDS | SERPINB1, HPN, DNPEP | EPHX1 2053/4885CASP2 466/4885POLB 733/4885 |
| US-10989715-B2 | Ultra bright dimeric or polymeric dyes with spacing linker groups | IK, MTCL3, RRM1 | EPHX1 4538/4885CASP2 4197/4885POLB 3224/4885 |
| US-20240226026-A1 | BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | PLTP, LNPK, PLIN3 | EPHX1 3199/4885CASP2 3008/4885POLB 1805/4885 |
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | UNG, DPYD, DUT | EPHX1 1534/4885CASP2 2514/4885POLB 14/4885 |
| US-10882838-B2 | Cannabinergic compounds and uses thereof | CNR2, CNR1, GPR18 | EPHX1 2454/4885CASP2 955/4885POLB 3968/4885 |
| US-10550073-B2 | Benzamide derivative | CYP3A5, ABCB1, CYP2D6 | EPHX1 1725/4885CASP2 2511/4885POLB 2174/4885 |
| US-20150133428-A1 | NOVEL SUBSTITUTED PYRAZOLO-PIPERAZINES AS CASEIN KINASE 1 D/E INHIBITORS | CSNK1E, CSNK1A1, CSNK1G1 | EPHX1 3735/4885CASP2 2653/4885POLB 3064/4885 |
| US-20210101878-A1 | Cannabinergic Compounds And Uses Thereof | CNR2, CNR1, GPR18 | EPHX1 2454/4885CASP2 955/4885POLB 3968/4885 |
| US-20160108016-A1 | Novel Cannabinergic Compounds and Uses Thereof | CNR2, CNR1, GPR18 | EPHX1 2164/4885CASP2 1085/4885POLB 3864/4885 |
| US-20130079326-A1 | N-PHENYL IMIDAZOLE CARBOXAMIDE INHIBITORS OF 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 | PDPK1, PDK1, PDK3 | EPHX1 4466/4885CASP2 1480/4885POLB 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.