Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393132 | 1.00 | NT5E (0.49) | NT5EADORA1ADORA3SMN1; SMN2ADORA2A | |
| SCHEMBL21384830 | 1.00 | NT5E (0.49) | NT5EADORA1ADORA3SMN1; SMN2ADORA2A | |
| SCHEMBL22220143 | 0.91 | ADORA1 (0.50) | ADORA1ADORA3SMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL6762689 | 0.91 | ADORA1 (0.50) | ADORA1ADORA3SMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL30867101 | 0.91 | ADORA1 (0.50) | ADORA1ADORA3SMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL21859282 | 0.91 | ADORA1 (0.50) | ADORA1ADORA3SMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL21859151 | 0.91 | ADORA1 (0.50) | ADORA1ADORA3SMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL25389125 | 0.89 | ADORA3 (0.58) | NT5EADORA1ADORA3SMN1; SMN2ADORA2A | |
| SCHEMBL24377184 | 0.89 | ADORA3 (0.58) | NT5EADORA1ADORA3SMN1; SMN2ADORA2A | |
| SCHEMBL19590291 | 0.89 | ADORA3 (0.58) | NT5EADORA1ADORA3SMN1; SMN2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242218-A1 | MULTIFUNCTIONAL CYCLIC DINUCLEOTIDE AND USE THEREOF | Tyligand Bioscience (Shanghai) Limited (CN) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022083584-A1 | MULTIFUNCTIONAL CYCLIC DINUCLEOTIDE AND USE THEREOF | 泰励生物科技（上海）有限公司 | 2022-04-28 | — | — | WO | disclosed |