Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357620 | 0.75 | ACHE (0.56) | ACHE | |
| SCHEMBL799113 | 0.75 | ACHE (0.56) | ACHE | |
| SCHEMBL18081189 | 0.75 | ACHE (0.56) | ACHE | |
| SCHEMBL18081196 | 0.75 | ACHE (0.56) | ACHE | |
| SCHEMBL21912376 | 0.74 | TP53 (0.41) | ACHE | |
| SCHEMBL357619 | 0.73 | ACHE (0.54) | ACHE | |
| SCHEMBL16943568 | 0.71 | ACHE (0.80) | ACHE | |
| SCHEMBL20846886 | 0.70 | ACHE (0.50) | ACHE | |
| SCHEMBL24940051 | 0.70 | ACHE (0.50) | ACHE | |
| SCHEMBL25920478 | 0.70 | ACHE (0.50) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086986-A1 | TREATMENT OF HEMATOLOGICAL MALIGNANCIES WITH INHIBITORS OF MENIN | KURA ONCOLOGY, INC. (US) | 2022-04-28 | — | — | WO | disclosed |