⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19157984 | 0.67 | MEN1 (0.35) | — | |
| SCHEMBL12574036 | 0.63 | — | — | |
| SCHEMBL761830 | 0.61 | — | — | |
| SCHEMBL24733451 | 0.57 | — | — | |
| SCHEMBL20011294 | 0.56 | — | — | |
| SCHEMBL27393141 | 0.54 | — | — | |
| SCHEMBL34975 | 0.54 | — | — | |
| SCHEMBL28505111 | 0.53 | — | — | |
| SCHEMBL30143565 | 0.53 | — | — | |
| SCHEMBL13057851 | 0.53 | MAOA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086986-A1 | TREATMENT OF HEMATOLOGICAL MALIGNANCIES WITH INHIBITORS OF MENIN | KURA ONCOLOGY, INC. (US) | 2022-04-28 | — | — | WO | disclosed |