Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 16/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21329689 | 0.79 | TYK2 (0.45) | TYK2JAK2JAK1ALOX5 | |
| SCHEMBL29562794 | 0.79 | TYK2 (0.45) | TYK2JAK2JAK1ALOX5 | |
| SCHEMBL21329691 | 0.79 | TYK2 (0.45) | TYK2JAK2JAK1ALOX5 | |
| SCHEMBL24377774 | 0.79 | TYK2 (0.47) | TYK2JAK2JAK1ALOX5 | |
| SCHEMBL29562754 | 0.79 | TYK2 (0.45) | TYK2JAK2JAK1ALOX5 | |
| SCHEMBL29563106 | 0.79 | TYK2 (0.47) | TYK2JAK2JAK1ALOX5 | |
| SCHEMBL21330284 | 0.79 | TYK2 (0.45) | TYK2JAK2JAK1ALOX5 | |
| SCHEMBL29017823 | 0.76 | TYK2 (0.44) | TYK2JAK2JAK1 | |
| SCHEMBL30374006 | 0.76 | TYK2 (0.44) | TYK2JAK2JAK1 | |
| SCHEMBL29546485 | 0.71 | TYK2 (0.41) | TYK2JAK2JAK1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249526-A | TYK2 selective inhibitors and uses thereof | 南京药石科技股份有限公司 | 2023-06-09 | — | — | CN | disclosed |
| WO-2022083560-A1 | TYK2 SELECTIVE INHIBITOR AND USE THEREOF | 南京药石科技股份有限公司 | 2022-04-28 | — | — | WO | disclosed |
| WO-2022083560-A1 | TYK2 SELECTIVE INHIBITOR AND USE THEREOF | 南京药石科技股份有限公司 | 2022-04-28 | — | — | WO | disclosed |