SCHEMBL24377872

SCHEMBL24377872

C=Cc1ccc2c(c1)C(=C)c1cc(OC(=O)C(=C)C)ccc1-2

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.40
KMT2A Q03164 3/20 0.38
ATM Q13315 1/20 0.38
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
TTR P02766 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22345623 0.89 ELANE (0.49) ELANEKMT2AATMKDM4EMEN1
SCHEMBL22352929 0.85 ELANE (0.37) ELANEKMT2AATMKDM4EMEN1
SCHEMBL22352941 0.83 ELANE (0.44) ELANEKMT2AATMKDM4EMAPT
SCHEMBL22353034 0.83 ELANE (0.51) ELANEKMT2AATMMEN1LMNA
SCHEMBL27053111 0.82 ELANE (0.41) ELANEKMT2AATMMAPT
SCHEMBL9607826 0.81 ELANE (0.45) ELANEKMT2AATMKDM4EMEN1
SCHEMBL22353041 0.81 ELANE (0.46) ELANEKMT2AATMLMNAMAPT
SCHEMBL22352782 0.80 ELANE (0.36) ELANEKMT2AATM
SCHEMBL5831972 0.79 ELANE (0.56) ELANEKMT2AATMKDM4EMEN1
SCHEMBL22353025 0.78 MAPT (0.41) ELANEKMT2AATMKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685863-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2023-06-27 US disclosed
US-11685863-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2023-06-27 US disclosed
US-20220127532-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127532-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS LPXN, VCL, LCP1 ELANE 1153/4885KMT2A 2566/4885ATM 1563/4885
US-11685863-B2 Polymerisable compounds and the use thereof in liquid-crystal displays LPXN, VCL, LCP1 ELANE 1153/4885KMT2A 2566/4885ATM 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.