Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22345623 | 0.89 | ELANE (0.49) | MAPTL3MBTL1ELANEKMT2AMEN1 | |
| SCHEMBL19670076 | 0.84 | ELANE (0.45) | MAPTL3MBTL1ELANEGPR174KMT2A | |
| SCHEMBL20112746 | 0.84 | ELANE (0.40) | MAPTL3MBTL1ELANEGPR174KMT2A | |
| SCHEMBL22353034 | 0.83 | ELANE (0.51) | MAPTELANEKMT2AMEN1ALDH1A1 | |
| SCHEMBL22352941 | 0.83 | ELANE (0.44) | MAPTL3MBTL1ELANEKMT2APOLB | |
| SCHEMBL22352930 | 0.82 | ELANE (0.35) | ELANEKMT2APOLBATMHTT | |
| SCHEMBL22353041 | 0.81 | ELANE (0.46) | MAPTELANEKMT2APOLBATM | |
| SCHEMBL27053111 | 0.80 | ELANE (0.41) | MAPTELANEKMT2AATM | |
| SCHEMBL20112833 | 0.80 | KMT2A (0.45) | MAPTL3MBTL1ELANEGPR174KMT2A | |
| SCHEMBL21469988 | 0.79 | MAPT (0.43) | MAPTL3MBTL1ELANEGPR174KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165394-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2020-08-20 | — | — | WO | disclosed |