Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | PAK4 | O96013 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | GRK5 | P34947 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22828545 | 0.77 | HTT (0.32) | MAP4K4PAK4CSF1RRETGRK5 | |
| SCHEMBL24378003 | 0.67 | L3MBTL1 (0.36) | — | |
| SCHEMBL5634584 | 0.65 | MEN1 (0.32) | — | |
| Methane SCHEMBL31113175 | 0.63 | JAK2 (0.37) | MAP4K4PAK4CSF1RRETGRK5 | |
| SCHEMBL46977 | 0.61 | — | — | |
| SCHEMBL19327434 | 0.60 | AURKA (0.32) | MAP4K4MAPK8TYRO3MAP4K2DYRK1A | |
| SCHEMBL13075093 | 0.58 | MAP4K4 (0.47) | MAP4K4DYRK1A | |
| SCHEMBL31665951 | 0.57 | DYRK1A (0.39) | MAP4K4CSF1RRETMAPK8ACVR1 | |
| SCHEMBL24718562 | 0.56 | GAA (0.43) | — | |
| SCHEMBL22828757 | 0.56 | HTT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988551-A1 | CDK KINASE INHIBITOR | Beijing Benicall Biotech Co., Ltd. (CN) | 2022-04-27 | — | — | EP | disclosed |