Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22436700 | 0.79 | CSNK2A1 (0.36) | LMNASMN1; SMN2CSNK2A1ALDH1A1 | |
| SCHEMBL30679098 | 0.79 | CSNK2A1 (0.36) | LMNASMN1; SMN2CSNK2A1ALDH1A1 | |
| SCHEMBL14043734 | 0.76 | CSNK2A1 (0.36) | LMNASMN1; SMN2CSNK2A1 | |
| SCHEMBL30679115 | 0.76 | CSNK2A1 (0.36) | LMNASMN1; SMN2CSNK2A1 | |
| SCHEMBL22436737 | 0.72 | CSNK2A1 (0.35) | CSNK2A1ALDH1A1 | |
| SCHEMBL30679095 | 0.72 | CSNK2A1 (0.35) | CSNK2A1ALDH1A1 | |
| SCHEMBL24593558 | 0.71 | NPC1 (0.31) | LMNASMN1; SMN2CSNK2A1 | |
| SCHEMBL22436767 | 0.70 | CSNK2A1 (0.31) | CSNK2A1ALDH1A1 | |
| SCHEMBL22436734 | 0.70 | NPC1 (0.31) | LMNASMN1; SMN2CSNK2A1ALDH1A1 | |
| SCHEMBL30679059 | 0.70 | NPC1 (0.31) | LMNASMN1; SMN2CSNK2A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458459-B1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AG (DE) | 2022-04-27 | — | — | EP | disclosed |