Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14043734 | 1.00 | CSNK2A1 (0.36) | CSNK2A1RAB9APOLBNPC1HTT | |
| SCHEMBL24593558 | 0.83 | NPC1 (0.31) | CSNK2A1RAB9APOLBNPC1HTT | |
| SCHEMBL16200374 | 0.79 | POLB (0.38) | RAB9APOLBNPC1SMN1; SMN2LMNA | |
| SCHEMBL30679098 | 0.79 | CSNK2A1 (0.36) | CSNK2A1RAB9APOLBNPC1HTT | |
| SCHEMBL22436700 | 0.79 | CSNK2A1 (0.36) | CSNK2A1RAB9APOLBNPC1HTT | |
| SCHEMBL22436737 | 0.76 | CSNK2A1 (0.35) | CSNK2A1 | |
| SCHEMBL22436748 | 0.76 | SMN1; SMN2 (0.34) | RAB9ASMN1; SMN2LMNA | |
| SCHEMBL30679061 | 0.76 | SMN1; SMN2 (0.34) | RAB9ASMN1; SMN2LMNA | |
| SCHEMBL24378064 | 0.76 | LMNA (0.32) | CSNK2A1SMN1; SMN2LMNA | |
| SCHEMBL30679095 | 0.76 | CSNK2A1 (0.35) | CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757884-B | Substituted macrocyclic indole derivatives | 拜耳股份公司 | 2023-12-19 | — | — | CN | disclosed |