SCHEMBL2437822

SCHEMBL2437822

CCC(Oc1cccc(CNCCC(c2ccc(Cl)cc2)c2nc3ccccc3o2)c1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 20/20 0.49
PPARD Q03181 18/20 0.49
PPARG P37231 15/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2441911 0.94 PPARA (0.52) PPARAPPARDPPARG
SCHEMBL2439070 0.90 PPARG (0.47) PPARAPPARDPPARG
SCHEMBL1009482 0.87 PPARA (0.53) PPARAPPARDPPARG
SCHEMBL6543517 0.86 PPARA (0.46) PPARAPPARD
SCHEMBL1008833 0.86 PPARA (0.52) PPARAPPARDPPARG
SCHEMBL6543048 0.85 PPARG (0.48) PPARAPPARDPPARG
SCHEMBL1010591 0.85 PPARA (0.49) PPARAPPARDPPARG
SCHEMBL2440050 0.84 PPARD (0.51) PPARAPPARDPPARG
SCHEMBL1009347 0.83 PPARA (0.51) PPARAPPARDPPARG
SCHEMBL1012218 0.82 PPARA (0.56) PPARAPPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1433786-A1 Benzoxazole compound and pharmaceutical composition containing the compound Kowa Company Ltd. (JP) 2004-06-30 EP claimed
US-6653334-B1 Electively activate peroxisome proliferator activated receptors KOWA CO., LTD. (JP) 2003-11-25 US claimed
EP-1433786-B1 Benzoxazole compound and pharmaceutical composition containing the compound KOWA CO (JP) 2011-09-21 EP disclosed
EP-1433786-A1 Benzoxazole compound and pharmaceutical composition containing the compound Kowa Company Ltd. (JP) 2004-06-30 EP disclosed
US-6653334-B1 Electively activate peroxisome proliferator activated receptors KOWA CO., LTD. (JP) 2003-11-25 US disclosed