Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.48 |
| ▸ | PPARA | Q07869 | 8/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543121 | 0.94 | PPARG (0.51) | PPARGPPARAPPARDALDH1A1P2RY14 | |
| SCHEMBL1012086 | 0.89 | PPARA (0.47) | PPARGPPARAPPARDPOLBMAPT | |
| SCHEMBL6542914 | 0.88 | PPARG (0.47) | PPARGPPARAPPARDMAPTCNR1 | |
| SCHEMBL6542900 | 0.87 | PPARG (0.51) | PPARGPPARAPPARDPOLBMAPT | |
| SCHEMBL2439070 | 0.87 | PPARG (0.47) | PPARGPPARAPPARDMAPTALDH1A1 | |
| SCHEMBL6543944 | 0.87 | PPARG (0.54) | PPARGPPARAPPARDMAPTKDM4E | |
| SCHEMBL6543517 | 0.86 | PPARA (0.46) | PPARAPPARDPOLBALDH1A1KDM4E | |
| SCHEMBL2437822 | 0.85 | PPARA (0.49) | PPARGPPARAPPARD | |
| SCHEMBL6544050 | 0.85 | PPARG (0.56) | PPARGPPARAPPARDMAPTKDM4E | |
| SCHEMBL1009457 | 0.85 | PPARA (0.51) | PPARGPPARAPPARDALDH1A1P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |