Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24668422 | 0.88 | CASP3 (0.49) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL10312386 | 0.87 | CASP3 (0.48) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL12510929 | 0.87 | CASP3 (0.48) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL1491454 | 0.86 | MDM4 (0.55) | CASP3MDM4TP53 | |
| SCHEMBL1491458 | 0.86 | MDM4 (0.55) | CASP3MDM4TP53 | |
| SCHEMBL29400299 | 0.86 | MDM4 (0.55) | CASP3MDM4TP53 | |
| SCHEMBL119702 | 0.86 | MDM4 (0.55) | CASP3MDM4TP53 | |
| SCHEMBL29401132 | 0.86 | MDM4 (0.55) | CASP3MDM4TP53 | |
| SCHEMBL12088806 | 0.85 | MDM4 (0.48) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL18120612 | 0.84 | CASP3 (0.45) | CASP3KMT2AMDM4TP53EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022084738-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2022-04-28 | — | — | WO | disclosed |