Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14412226 | 0.85 | RAB9A (0.59) | NOTUMMAPTRAB9ANPC1ATM | |
| SCHEMBL16202076 | 0.83 | MAPT (0.46) | NOTUMMAPTRAB9ANPC1ATM | |
| SCHEMBL28020284 | 0.83 | NOTUM (0.57) | NOTUMMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17883765 | 0.81 | NOTUM (0.55) | NOTUMMAPTNPC1ACHECYP1A2 | |
| SCHEMBL30264186 | 0.81 | NOTUM (0.55) | NOTUMMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15352892 | 0.81 | NOTUM (0.55) | NOTUMMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27636269 | 0.81 | NOTUM (0.55) | NOTUMMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28504786 | 0.81 | NOTUM (0.51) | NOTUMMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL598042 | 0.80 | HTT (0.53) | MAPTRAB9ANPC1ATMSMN1; SMN2 | |
| SCHEMBL5101204 | 0.80 | MEN1 (0.56) | MAPTRAB9ANPC1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086993-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC (US) | 2022-04-28 | — | — | WO | disclosed |