Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005502 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBKDM4ERECQL | |
| SCHEMBL15082731 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBKDM4ERECQL | |
| SCHEMBL25922720 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBKDM4ERECQL | |
| SCHEMBL7071314 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBKDM4ERECQL | |
| SCHEMBL19249028 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBKDM4ERECQL | |
| SCHEMBL22269102 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBKDM4ERECQL | |
| SCHEMBL126241 | 0.94 | — | — | |
| SCHEMBL20075870 | 0.93 | NPC1 (0.35) | ALDH1A1TSHRTHRBKDM4EMEN1 | |
| SCHEMBL23651532 | 0.93 | KDM4E (0.42) | ALDH1A1TSHRTHRBKDM4ERECQL | |
| Hydrochloric Acid SCHEMBL7085471 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087243-A1 | ANTI-FGFR2 ANTIBODIES AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |