Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.30 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27009148 | 0.76 | PDE10A (0.40) | PDE10ACKS1BSKP2 | |
| SCHEMBL24378542 | 0.71 | CYP1A2 (0.42) | PDE10A | |
| SCHEMBL20511355 | 0.69 | TDP1 (0.49) | PDE10A | |
| SCHEMBL20511288 | 0.68 | SMN1; SMN2 (0.47) | PDE10A | |
| SCHEMBL7984951 | 0.67 | SMN1; SMN2 (0.33) | PDE10A | |
| SCHEMBL9680379 | 0.65 | KDM4E (0.46) | PDE10A | |
| SCHEMBL23413440 | 0.65 | KDM4E (0.59) | — | |
| SCHEMBL21630207 | 0.62 | HSD11B1 (0.42) | — | |
| SCHEMBL23649060 | 0.61 | PDE10A (0.50) | PDE10A | |
| SCHEMBL1934522 | 0.60 | PDE10A (0.48) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086993-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC (US) | 2022-04-28 | — | — | WO | disclosed |