Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 17/20 | 1.00 |
| ▸ | PRSS2 | P07478 | 17/20 | 1.00 |
| ▸ | PRSS3 | P35030 | 17/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088981 | 0.67 | — | — | |
| SCHEMBL614082 | 0.63 | — | — | |
| SCHEMBL41865 | 0.63 | — | — | |
| SCHEMBL2565951 | 0.63 | — | — | |
| SCHEMBL7403339 | 0.63 | — | — | |
| SCHEMBL13449747 | 0.61 | F2 (0.56) | F2PRSS1PRSS2PRSS3BLM | |
| SCHEMBL20953594 | 0.61 | F2 (0.44) | F2PRSS1PRSS2PRSS3BLM | |
| SCHEMBL14036407 | 0.61 | — | — | |
| Acetamide SCHEMBL28743112 | 0.59 | LMNA (0.50) | F2PRSS1PRSS2PRSS3BLM | |
| SCHEMBL28611906 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988120-A1 | NHE3-BINDING COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2022-04-27 | — | — | EP | disclosed |