SCHEMBL24378724

SCHEMBL24378724

CC(C)(C)C(=O)OC(C)(C)C(=O)OC1CCC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.41
HTT P42858 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
EPHX1 P07099 2/20 0.34
CHRM3 P20309 11/20 0.33
NAAA Q02083 2/20 0.33
CHRM2 P08172 6/20 0.31
LMNA P02545 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
SLC6A4 P31645 1/20 0.31
KCNH2 Q12809 1/20 0.31
SLC22A1 O15245 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23323285 0.96 CYP19A1 (0.44) CYP19A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL13073268 0.86 CYP19A1 (0.46) CYP19A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL1682649 0.81 CYP19A1 (0.50) CYP19A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL4675444 0.81 CYP19A1 (0.44) CYP19A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL4675441 0.81 CYP19A1 (0.44) CYP19A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL23334601 0.80 NAAA (0.40) CYP19A1HTTRAB9ASMN1; SMN2EPHX1
SCHEMBL28317353 0.79 CYP19A1 (0.53) CYP19A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL2182130 0.79 CYP19A1 (0.53) CYP19A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL3709223 0.79 CYP19A1 (0.46) CYP19A1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL7064390 0.79 CYP19A1 (0.46) CYP19A1HTTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3816149-B1 ISOBUTYRIC ESTER COMPOUND HAVING AN ISOBUTYRYLOXY GROUP OR PIVALOYLOXY GROUP AT ALPHA POSITION, AND PERFUME COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2022-04-27 EP disclosed