SCHEMBL24379650

SCHEMBL24379650

CCC(C)(CCNC(C)(C)C)OCCC(C)(C)n1cc(CN2CCS(=O)(=O)CC2)nn1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20988715 0.90 KMT2A (0.35) CYP1A2CYP2C19KMT2A
SCHEMBL22209541 0.85 CYP1A2 (0.33) CYP1A2CYP2C19KMT2A
SCHEMBL24029347 0.81 KMT2A (0.38) CYP1A2CYP2C19KMT2A
SCHEMBL22138141 0.80 KMT2A (0.36) CYP1A2CYP2C19KMT2A
SCHEMBL19734913 0.77 CYP1A2 (0.33) CYP1A2CYP2C19KMT2A
SCHEMBL19708674 0.75 CYP1A2 (0.31) CYP1A2CYP2C19KMT2A
SCHEMBL20988992 0.71 DRD2 (0.43) CYP1A2CYP2C19KMT2A
SCHEMBL19302623 0.71 DRD2 (0.43) CYP1A2CYP2C19KMT2A
SCHEMBL22356547 0.65
SCHEMBL22358512 0.64 DRD2 (0.43) CYP1A2CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11318231-B2 Anti-inflammatory coatings to improve biocompatibility of neurological implants MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-05-03 US disclosed