SCHEMBL2438183

SCHEMBL2438183

N#CC[Na]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28113085 0.67
Water SCHEMBL27883112 0.59
SCHEMBL1078946 0.59 ALDH1A1 (0.46)
SCHEMBL60898 0.59
SCHEMBL16037462 0.59 ALDH1A1 (1.00)
SCHEMBL56391 0.59
SCHEMBL7016041 0.56
Lithium SCHEMBL10525716 0.56
SCHEMBL2683512 0.56
SCHEMBL16585787 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2006523699-A 2006-10-19 JP claimed
US-20060194838-A1 Polymorphic form of montelukast sodium MERCK SHARP & DOHME CORP. 2006-08-31 US claimed
EP-1633357-A1 POLYMORPHIC FORM OF MONTELUKAST SODIUM Merck & Co., Inc. (US) 2006-03-15 EP claimed
WO-2004091618-A1 POLYMORPHIC FORM OF MONTELUKAST SODIUM MERCK FROSST CANADA LTD. (CA) 2004-10-28 WO claimed
EP-4743462-A1 COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS Tay Therapeutics Limited (GB) 2026-05-20 EP disclosed
US-20250101034-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2025-03-27 US disclosed
WO-2025012643-A1 COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS Tay Therapeutics Limited (GB) 2025-01-16 WO disclosed
EP-4426704-A1 CONDENSED PYRIDAZINE AMINE DERIVATIVES TREATING SCA3 Skyhawk Therapeutics, Inc. (US) 2024-09-11 EP disclosed
WO-2023081857-A1 CONDENSED PYRIDAZINE AMINE DERIVATIVES TREATING SCA3 SKYHAWK THERAPEUTICS, INC. (US) 2023-05-11 WO disclosed
US-20140194349-A1 HIV Protease Inhibiting Compounds ABBVIE INC. (US) 2014-07-10 US disclosed
EP-1697344-B1 HIV PROTEASE INHIBITING COMPOUNDS ABBOTT LAB (US) 2011-09-28 EP disclosed
EP-2266971-A2 Hiv protease inhibiting compounds Abbott Laboratories (US) 2010-12-29 EP disclosed
US-7834043-B2 Prevent reproduct of aids virus ABBOTT LABORATORIES (US) 2010-11-16 US disclosed
US-20100249181-A1 HIV Protease Inhibiting Compounds ABBOTT LABORATORIES (US) 2010-09-30 US disclosed
EP-1697344-A2 HIV PROTEASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 2006-09-06 EP disclosed
US-20050148623-A1 Prevent reproduct of aids virus ABBVIE INC. 2005-07-07 US disclosed
WO-2005058841-A2 HIV PROTEASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 2005-06-30 WO disclosed
US-20050131017-A1 HIV protease inhibiting compounds ABBOTT LABORATORIES 2005-06-16 US disclosed