Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18783452 | 0.88 | AVPR2 (0.47) | AVPR2AVPR1ACNR1 | |
| SCHEMBL8232476 | 0.83 | AVPR2 (0.61) | AVPR2AVPR1ACYP1A2GAACYP2C19 | |
| SCHEMBL2438261 | 0.78 | AVPR2 (0.49) | AVPR2AVPR1ACNR1MAPTLMNA | |
| SCHEMBL18783440 | 0.78 | AVPR2 (0.56) | AVPR2AVPR1ACNR1MRGPRX4 | |
| SCHEMBL2500581 | 0.77 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL8227135 | 0.76 | AVPR2 (0.47) | AVPR2AVPR1ACYP1A2GAACYP2C19 | |
| SCHEMBL8233090 | 0.76 | AVPR2 (0.49) | AVPR2AVPR1ACYP1A2GAACYP2C19 | |
| SCHEMBL8235892 | 0.75 | AVPR2 (0.49) | AVPR2AVPR1ACYP1A2GAACYP2C19 | |
| SCHEMBL8739607 | 0.75 | AVPR2 (0.53) | AVPR2AVPR1ACYP1A2GAACYP2C19 | |
| SCHEMBL18783444 | 0.74 | AVPR2 (0.45) | AVPR2AVPR1ACMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539326-B1 | BISARYL-BONDED ARYLTRIAZOLONES AND USE THEREOF | BAYER IP GMBH (DE) | 2017-05-03 | — | — | EP | disclosed |
| WO-2011104322-A1 | BISARYL-BONDED ARYLTRIAZOLONES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-09-01 | — | — | WO | disclosed |