SCHEMBL24383294

SCHEMBL24383294

COc1ccc(C(OCC2CC(O)CN2C(=O)CCCCCCC(=O)O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 7/20 0.42
SLC6A1 P30531 3/20 0.42
PTGFR P43088 1/20 0.38
SLC6A12 P48065 2/20 0.38
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
KMT2A Q03164 1/20 0.38
SLC6A13 Q9NSD5 1/20 0.38
PDE4B Q07343 1/20 0.37
TYMP P19971 1/20 0.36
CYP2J2 P51589 1/20 0.35
BRD4 O60885 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
SAE1 Q9UBE0 1/20 0.35
UBA2 Q9UBT2 1/20 0.35
KIF11 P52732 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16843276 1.00 SLC6A11 (0.42) SLC6A11SLC6A1PTGFRSLC6A12MEN1
SCHEMBL17231722 1.00 SLC6A11 (0.42) SLC6A11SLC6A1PTGFRSLC6A12MEN1
SCHEMBL9604514 1.00 SLC6A11 (0.42) SLC6A11SLC6A1PTGFRSLC6A12MEN1
SCHEMBL26302691 0.94 SLC6A11 (0.42) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL14978147 0.94 SLC6A11 (0.42) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL14977891 0.94 SLC6A11 (0.42) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL26302685 0.94 SLC6A11 (0.42) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL26302681 0.94 SLC6A11 (0.42) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL9908638 0.94 SLC6A11 (0.42) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL16248722 0.93 SLC6A11 (0.44) SLC6A11SLC6A1SLC6A12MEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11840691-B2 Compound and application thereof KYLONOVA (XIAMEN) BIOPHARMA CO., LTD. (CN) 2023-12-12 US disclosed
US-11840691-B2 Compound and application thereof KYLONOVA (XIAMEN) BIOPHARMA CO., LTD. (CN) 2023-12-12 US disclosed
US-20230374513-A1 NOVEL COMPOUND AND APPLICATION THEREOF KYLONOVA (XIAMEN) BIOPHARMA CO., LTD. (CN) 2023-11-23 US disclosed
US-20230374513-A1 NOVEL COMPOUND AND APPLICATION THEREOF KYLONOVA (XIAMEN) BIOPHARMA CO., LTD. (CN) 2023-11-23 US disclosed
EP-3992291-A1 NOVEL COMPOUND AND APPLICATION THEREOF Kylonova (Xiamen) Biopharma Co., Ltd. (CN) 2022-05-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230374513-A1 NOVEL COMPOUND AND APPLICATION THEREOF GALNT6, GALNT3, GALNT14 SLC6A11 3947/4885SLC6A1 4032/4885PTGFR 3537/4885
US-11840691-B2 Compound and application thereof GALNT6, GALNT3, GALNT14 SLC6A11 3924/4885SLC6A1 3975/4885PTGFR 3662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.