SCHEMBL2438441

SCHEMBL2438441

O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.[Pd]

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.95
CYP2C9 P11712 3/20 0.95
F3 P13726 3/20 0.95
CYP1A2 P05177 3/20 0.95
PLIN1 O60240 2/20 0.95
LMNA P02545 2/20 0.95
RECQL P46063 2/20 0.95
PLIN5 Q00G26 2/20 0.95
ABHD5 Q8WTS1 2/20 0.95
CYP2D6 P10635 2/20 0.95
ALDH1A1 P00352 2/20 0.95
SMN1; SMN2 Q16637 1/20 0.95
HDAC3 O15379 2/20 0.70
HDAC4 P56524 2/20 0.70
HDAC1 Q13547 2/20 0.70
HDAC2 Q92769 2/20 0.70
HDAC8 Q9BY41 2/20 0.70
HDAC6 Q9UBN7 2/20 0.70
TNKS O95271 1/20 0.70
HCAR2 Q8TDS4 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL546073 1.00 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL7512289 1.00 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL509571 1.00 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL1646390 1.00 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL5111 1.00 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL14832106 1.00 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL18039478 1.00 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL187662 1.00 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL21879664 1.00 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL2639578 1.00 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3119 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700396-B Heteroaryl pyrimidine derivative containing pyridine-benzene ring structure, and preparation method and application thereof FUDAN UNIVERSITY (CN) 2026-05-26 CN claimed
US-20260092322-A1 METHODS AND COMPOSITIONS FOR DEPROTECTION OF REVERSIBLY TERMINATED NUCLEOTIDES 10X GENOMICS INC (US) 2026-04-02 US claimed
EP-4713315-A1 PROCESS FOR THE PREPARATION OF DEUCRAVACITINIB, AND CRYSTALLINE FORMS THEREOF Alivus Life Sciences Limited (IN) 2026-03-25 EP claimed
US-12577236-B2 Processes for preparation of Tezacaftor LAURUS LABS LIMITED (IN) 2026-03-17 US claimed
US-12568972-B2 Pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2026-03-10 US claimed
US-20260062361-A1 PROCESS FOR THE PREPARATION OF BIO-BASED OLEFINS FROM PRIMARY ALCOHOL BASF SE (DE) 2026-03-05 US claimed
EP-4567021-B1 METHOD FOR THE ALKOXYCARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS USING CO2 AND A ZINC COMPOUND EVONIK OXENO GMBH & CO KG (DE) 2026-03-04 EP claimed
EP-4702008-A1 ARENE-CHLORINATION USING CHLORINATED WASTE ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2026-03-04 EP claimed
EP-4688717-A1 PALLADIUM-CATALYZED CHEMOSELECTIVE MONO-ALPHA-ARYLATION OF O-PROTECTED HYDROXYACETONE Bayer Aktiengesellschaft (DE) 2026-02-11 EP claimed
US-12522589-B2 Synthesis of CRAC channel inhibitors CALCIMEDICA, INC. (US) 2026-01-13 US claimed
US-11312677-B2 Synthesis of building blocks and feedstocks for manufacturing renewable polymers QATAR FOUNDATION FOR EDUCATION, SCIENCE AND COMMUNITY DEVELOPMENT (QA) 2022-04-26 US claimed
CN-112479920-B Axis-like chiral anilide compound and preparation method and application thereof 复旦大学 2022-04-01 CN claimed
CN-114085213-B Preparation method of ARV-471 苏州国匡医药科技有限公司 2022-03-25 CN claimed
CN-113698402-B Synthetic method and application of natural alkaloid Arbornamine with anti-inflammatory activity 华南理工大学 2022-03-25 CN claimed
US-20220081413-A1 SYNTHESIS OF QUINAZOLINE COMPOUNDS GENENTECH, INC. (US) 2022-03-17 US claimed
CN-110357832-B Preparation method of aromatic amine compound, EphB4 kinase inhibitor and derivatives thereof 武汉大学 2022-03-15 CN claimed
CN-114149382-A Ritonavir impurity and preparation method thereof 乳源瑶族自治县东阳光生物科技有限公司 2022-03-08 CN claimed
CN-114085213-A Preparation method of ARV-471 苏州国匡医药科技有限公司 2022-02-25 CN claimed
WO-2022035790-A1 SYNTHESIS OF QUINAZOLINE COMPOUNDS GENENTECH, INC. (US) 2022-02-17 WO claimed
US-6107521-A Process for the preparation of secondary amines CELGRO (US) 2000-08-22 US claimed