Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.95 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.95 |
| ▸ | F3 | P13726 | 3/20 | 0.95 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.95 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.95 |
| ▸ | LMNA | P02545 | 2/20 | 0.95 |
| ▸ | RECQL | P46063 | 2/20 | 0.95 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.95 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.95 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.95 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.70 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.70 |
| ▸ | TNKS | O95271 | 1/20 | 0.70 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546073 | 1.00 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL7512289 | 1.00 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL509571 | 1.00 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL5111 | 1.00 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL14832106 | 1.00 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL2438441 | 1.00 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL18039478 | 1.00 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL187662 | 1.00 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL21879664 | 1.00 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL2639578 | 1.00 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530122-A | Phosphine ligand and application thereof in synthesizing propionate through vinylcarbonyl | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530116-A | Method for synthesizing acrylic ester by carbonylation of acetylene | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530276-A | Phosphine ligand and application thereof in synthesizing acrylic ester by acetylene carbonyl | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530115-A | Method for synthesizing acrylic ester by carbonylation of acetylene | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530278-A | Phosphine ligand and application thereof in synthesizing acrylic ester by acetylene carbonyl | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530117-A | Method for synthesizing acrylic ester by carbonylation of acetylene | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530280-A | Asymmetric diphosphine ligand and application thereof in synthesizing acrylic ester by acetylene carbonylation | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530121-A | Method for synthesizing propionate by ethylene carbonylation | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530118-A | Method for synthesizing acrylic ester by carbonylation of acetylene | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530120-A | Method for synthesizing propionate by ethylene carbonylation | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530119-A | Method for synthesizing propionate by ethylene carbonylation | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-118530117-A | Method for synthesizing acrylic ester by carbonylation of acetylene | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | disclosed |
| CN-118530122-A | Phosphine ligand and application thereof in synthesizing propionate through vinylcarbonyl | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | disclosed |
| CN-118530119-A | Method for synthesizing propionate by ethylene carbonylation | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | disclosed |
| CN-118530121-A | Method for synthesizing propionate by ethylene carbonylation | 中国科学院上海有机化学研究所 | 2024-08-23 | — | — | CN | disclosed |
| US-20090192134-A1 | Compounds | MEGHANI PREMJI | 2009-07-30 | — | — | US | disclosed |
| EP-2066659-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2009-06-10 | — | — | EP | disclosed |
| US-20080153843-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2008-06-26 | — | — | US | disclosed |
| US-20080096860-A1 | Pyrimidine Sulphonamide Derivatives as Chemokine Receptor Modulators | ASTRAZENECA AB (SE) | 2008-04-24 | — | — | US | disclosed |
| WO-2008040492-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192134-A1 | Compounds | CCL11, CCL2, CCL5 | MAPT 2652/4885CYP2C9 1206/4885F3 1070/4885 |
| US-20080153843-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | SULT2A1, STS, SULT1A1 | MAPT 2195/4885CYP2C9 196/4885F3 2461/4885 |
| US-20080096860-A1 | Pyrimidine Sulphonamide Derivatives as Chemokine Receptor Modulators | CXCR1, CCR5, ACKR3 | MAPT 4176/4885CYP2C9 2581/4885F3 3648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.