Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17466146 | 0.83 | CD44 (0.37) | ALOX15ALDH1A1CYP1A2CASP7HIF1A | |
| SCHEMBL30030017 | 0.82 | DPP4 (0.33) | ALOX15ALOX12 | |
| SCHEMBL14774772 | 0.82 | DPP4 (0.33) | ALOX15ALOX12 | |
| SCHEMBL9886100 | 0.81 | GRIN2D (0.42) | DHFR | |
| SCHEMBL17466153 | 0.80 | CD44 (0.41) | ALOX15ALOX12ALDH1A1CYP1A2CASP7 | |
| SCHEMBL19433173 | 0.80 | DPP4 (0.36) | ALOX15ALDH1A1CYP1A2CASP7HIF1A | |
| SCHEMBL31459934 | 0.78 | GRIN2D (0.36) | — | |
| SCHEMBL26971076 | 0.77 | POLB (0.33) | ALOX15ALOX12ALDH1A1CYP1A2CASP7 | |
| SCHEMBL28490129 | 0.77 | KDM1A (0.38) | — | |
| SCHEMBL488821 | 0.76 | GPR84 (0.37) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3992189-A1 | QUINAZOLINE AND CINNOLINE DERIVATIVES AS DNA-PK INHIBITOR | Medshine Discovery Inc. (CN) | 2022-05-04 | — | — | EP | disclosed |