SCHEMBL24385149

SCHEMBL24385149

C1=CCc2c(n(-c3ccccc3)c3ccc(N(c4ccc(-c5ccc(N(c6cccc(-c7ccccc7)c6)c6ccc7c(c6)c6ccccc6n7-c6ccccc6)cc5)cc4)c4cccc(-c5ccccc5)c4)cc23)C=C1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TSPO P30536 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23050574 0.86 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL16353116 0.84 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPO
SCHEMBL13725866 0.84 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPO
SCHEMBL16158320 0.84 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPO
SCHEMBL8928169 0.84 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPO
SCHEMBL16158237 0.84 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPO
SCHEMBL16158268 0.84 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPO
SCHEMBL16158241 0.84 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPO
SCHEMBL16158396 0.84 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPO
SCHEMBL17740668 0.84 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3992200-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2022-05-04 EP disclosed