Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 1.00 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30423726 | 1.00 | MPI (1.00) | MPITRPV1TSHRALOX5MEN1 | |
| SCHEMBL4142034 | 0.86 | MPI (0.76) | MPITRPV1TSHRALOX5MEN1 | |
| SCHEMBL9647788 | 0.85 | MPI (0.73) | MPITRPV1TSHRALOX5MEN1 | |
| SCHEMBL28345280 | 0.85 | MPI (0.73) | MPITRPV1TSHRALOX5MEN1 | |
| SCHEMBL28345371 | 0.85 | MPI (0.73) | MPITRPV1TSHRALOX5MEN1 | |
| SCHEMBL29552755 | 0.85 | MPI (0.73) | MPITRPV1TSHRALOX5MEN1 | |
| SCHEMBL28396372 | 0.85 | MPI (0.73) | MPITRPV1TSHRALOX5MEN1 | |
| SCHEMBL11279279 | 0.85 | MPI (0.73) | MPITRPV1TSHRALOX5MEN1 | |
| SCHEMBL9645125 | 0.81 | MPI (0.67) | MPITRPV1ALOX5MEN1KMT2A | |
| SCHEMBL9647842 | 0.81 | MPI (0.67) | MPITRPV1TSHRALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110655521-A | 12H-indazole [2,1-a ] cinnoline-12-ketone compound and application thereof | 浙江工业大学 | 2020-01-07 | — | — | CN | claimed |
| CN-110742892-B | Application of 12H-indazole [2,1-a ] cinnoline-12-ketone compound | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-110655521-B | 12H-indazole [2,1-a ] cinnoline-12-ketone compound and application thereof | 浙江工业大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-110742892-A | Application of 12H-indazole [2,1-a ] cinnoline-12-ketone compound | 浙江工业大学 | 2020-02-04 | — | — | CN | disclosed |
| CN-110655521-A | 12H-indazole [2,1-a ] cinnoline-12-ketone compound and application thereof | 浙江工业大学 | 2020-01-07 | — | — | CN | disclosed |
| US-20170095485-A1 | METHODS AND COMPOUNDS TO INHIBIT ENVELOPED VIRUS RELEASE | The Research Foundation for the State of University of New York | 2017-04-06 | — | — | US | disclosed |
| US-20170095485-A1 | METHODS AND COMPOUNDS TO INHIBIT ENVELOPED VIRUS RELEASE | The Research Foundation for the State of University of New York | 2017-04-06 | — | — | US | disclosed |
| US-20140179637-A1 | METHODS AND COMPOUNDS TO INHIBIT ENVELOPED VIRUS RELEASE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-06-26 | — | — | US | disclosed |
| US-20140179637-A1 | METHODS AND COMPOUNDS TO INHIBIT ENVELOPED VIRUS RELEASE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-06-26 | — | — | US | disclosed |
| US-20110257233-A1 | BENZOISOTHIAZOLONES AS INHIBITORS OF PHOSPHOMANNOSE ISOMERASE | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-10-20 | — | — | US | disclosed |
| WO-2011116355-A2 | BENZOISOTHIAZOLONES AS INHIBITORS OF PHOSPHOMANNOSE ISOMERASE | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170095485-A1 | METHODS AND COMPOUNDS TO INHIBIT ENVELOPED VIRUS RELEASE | SARS1, EEA1, ZC3HAV1 | MPI 840/4885TRPV1 3204/4885TSHR 4452/4885 |
| US-20140179637-A1 | METHODS AND COMPOUNDS TO INHIBIT ENVELOPED VIRUS RELEASE | SARS1, EEA1, ZC3HAV1 | MPI 840/4885TRPV1 3204/4885TSHR 4452/4885 |
| US-20110257233-A1 | BENZOISOTHIAZOLONES AS INHIBITORS OF PHOSPHOMANNOSE ISOMERASE | MPI, PMM2, GPI | MPI 1/4885TRPV1 4837/4885TSHR 4298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.