Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24529289 | 0.86 | HCRTR2 (0.35) | HCRTR2 | |
| SCHEMBL24387354 | 0.84 | HCRTR2 (0.34) | HCRTR2 | |
| SCHEMBL24387358 | 0.83 | HCRTR2 (0.34) | HCRTR2 | |
| SCHEMBL29749929 | 0.83 | HCRTR2 (0.34) | HCRTR2 | |
| SCHEMBL24529331 | 0.80 | HCRTR2 (0.34) | HCRTR2 | |
| SCHEMBL29749915 | 0.79 | HCRTR2 (0.33) | HCRTR2 | |
| SCHEMBL26911143 | 0.79 | HCRTR2 (0.33) | HCRTR2 | |
| SCHEMBL26911139 | 0.79 | HCRTR2 (0.35) | HCRTR2 | |
| SCHEMBL24387558 | 0.79 | HCRTR2 (0.33) | HCRTR2 | |
| Hydrochloric Acid SCHEMBL26911052 | 0.78 | HCRTR2 (0.33) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4262788-A1 | UREA OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-4236938-A1 | MACROCYCLIC UREA OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2023-09-06 | — | — | EP | disclosed |
| CN-116600803-A | Macrocyclic urea orexin receptor agonists | 默沙东有限责任公司 | 2023-08-15 | — | — | CN | disclosed |
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022094012-A1 | MACROCYCLIC UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-05-05 | — | — | WO | disclosed |
| WO-2022094012-A1 | MACROCYCLIC UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-05-05 | — | — | WO | disclosed |