Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.60 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL24418 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL5185312 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL7396011 | 0.95 | SLC22A1 (0.60) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL243898 | 0.95 | SLC22A1 (0.67) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrahexylammonium SCHEMBL3641187 | 0.93 | SLC22A1 (0.62) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Sulfuric Acid SCHEMBL9792101 | 0.93 | SLC22A1 (0.62) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrapentylammonium SCHEMBL6261128 | 0.92 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL28646343 | 0.92 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL20550033 | 0.92 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL9795123 | 0.92 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566574-B2 | Catalyst mixtures | DIOXIDE MATERIALS, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| EP-2588647-A1 | NOVEL CATALYST MIXTURES | Dioxide Materials Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| US-20120308903-A1 | Novel Catalyst Mixtures | DIOXIDE MATERIALS, INC | 2012-12-06 | — | — | US | disclosed |
| WO-2012006240-A1 | NOVEL CATALYST MIXTURES | DIOXIDE MATERIALS, INC. (US) | 2012-01-12 | — | — | WO | disclosed |