SCHEMBL24390494

SCHEMBL24390494

NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)NS

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.66
▸ CCKAR P32238 10/20 0.46
▸ CCKBR P32239 10/20 0.46
▸ FOLH1 Q04609 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24390495 1.00 GLP1R (0.66) GLP1RCCKARCCKBRFOLH1
SCHEMBL16192884 0.99 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL21099729 0.99 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL19867247 0.99 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL21099731 0.99 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL16382334 0.94 GLP1R (0.70) GLP1RCCKARCCKBRFOLH1
SCHEMBL24363619 0.94 GLP1R (0.70) GLP1RCCKARCCKBRFOLH1
SCHEMBL16382406 0.94 GLP1R (0.70) GLP1RCCKARCCKBRFOLH1
SCHEMBL6891947 0.94 GLP1R (0.70) GLP1RCCKARCCKBRFOLH1
SCHEMBL21100103 0.94 GLP1R (0.60) GLP1RCCKARCCKBRFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346961-A1 GLP-1 AND GIP RECEPTOR CO-AGONISTS NOVO NORDISK A/S (DK) 2023-11-02 — — US disclosed
WO-2022090447-A1 GLP-1, GIP AND GLUCAGON RECEPTOR TRIPLE AGONISTS NOVO NORDISK A/S (DK) 2022-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346961-A1 GLP-1 AND GIP RECEPTOR CO-AGONISTS GLP1R, GIPR, GCGR GLP1R 1/4885CCKAR 26/4885CCKBR 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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