SCHEMBL21100103

SCHEMBL21100103

NC(=O)[C@H](CCCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O)C(O)O)NS

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.60
▸ CCKAR P32238 10/20 0.44
▸ CCKBR P32239 10/20 0.44
▸ FOLH1 Q04609 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19867247 0.95 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL21099729 0.95 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL21099731 0.95 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL16192884 0.95 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL24390494 0.94 GLP1R (0.66) GLP1RCCKARCCKBRFOLH1
SCHEMBL24390495 0.94 GLP1R (0.66) GLP1RCCKARCCKBRFOLH1
SCHEMBL20651333 0.92 GLP1R (0.60) GLP1RCCKARCCKBRFOLH1
SCHEMBL19867174 0.90 GLP1R (0.58) GLP1RCCKARCCKBRFOLH1
SCHEMBL16192891 0.89 GLP1R (0.62) GLP1RCCKARCCKBRFOLH1
SCHEMBL16382334 0.89 GLP1R (0.70) GLP1RCCKARCCKBRFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2986313-B1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE NOVO NORDISK AS (DK) 2019-06-12 — — EP disclosed
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