Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.36 |
| ▸ | GRM8 | O00222 | 2/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24392656 | 0.84 | GRM8 (0.35) | KDM4EALDH1A1L3MBTL1CYP1A2GRM8 | |
| SCHEMBL24393151 | 0.79 | HTT (0.38) | ALDH1A1CYP1A2MAPTLMNATP53 | |
| SCHEMBL24393120 | 0.78 | POLB (0.37) | KDM4EALDH1A1L3MBTL1CYP1A2LMNA | |
| SCHEMBL24392336 | 0.71 | ENPP1 (0.32) | — | |
| SCHEMBL24392654 | 0.66 | SMN1; SMN2 (0.33) | ALDH1A1PDE10A | |
| SCHEMBL24393125 | 0.65 | CASR (0.33) | CYP1A2GRM8GRM7MAPTLMNA | |
| SCHEMBL24391784 | 0.64 | KDM4E (0.32) | KDM4EALDH1A1L3MBTL1HTT | |
| SCHEMBL19194448 | 0.62 | DHODH (0.50) | ALDH1A1 | |
| SCHEMBL20088561 | 0.60 | PDE10A (0.38) | KDM4ELMNATP53PDE10AHTT | |
| SCHEMBL19560852 | 0.60 | PDE10A (0.52) | PDE10AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022091048-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (ENPP1) INHIBITORS AND USES THEREOF | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2022-05-05 | — | — | WO | disclosed |