Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29503576 | 1.00 | USP2 (0.49) | USP2SMN1; SMN2RECQLCCR2EPHX2 | |
| SCHEMBL994040 | 0.92 | USP2 (0.55) | USP2SMN1; SMN2RECQLCCR2EPHX2 | |
| SCHEMBL18406799 | 0.89 | USP2 (0.50) | USP2SMN1; SMN2RECQLEPHX2GPR119 | |
| SCHEMBL14314348 | 0.82 | USP2 (0.44) | USP2SMN1; SMN2RECQLEPHX2GPR119 | |
| SCHEMBL2398369 | 0.82 | USP2 (0.59) | USP2SMN1; SMN2RECQLEPHX2CTSS | |
| SCHEMBL14306563 | 0.81 | HPGD (0.43) | USP2SMN1; SMN2EPHX2CTSSGPR119 | |
| SCHEMBL3665241 | 0.81 | HPGD (0.43) | USP2SMN1; SMN2EPHX2CTSSGPR119 | |
| SCHEMBL14314342 | 0.80 | EPHX2 (0.42) | USP2SMN1; SMN2EPHX2GPR119CTSK | |
| SCHEMBL29503574 | 0.80 | USP2 (0.55) | USP2SMN1; SMN2RECQLCCR2EPHX2 | |
| SCHEMBL24394305 | 0.80 | USP2 (0.55) | USP2SMN1; SMN2RECQLCCR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390727-A | N-linked isoquinolinamides as LRRK2 inhibitors, pharmaceutical compositions and uses thereof | 默沙东有限责任公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2022093881-A1 | N-LINKED ISOQUINOLINE AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2022-05-05 | — | — | WO | disclosed |