SCHEMBL3665241

SCHEMBL3665241

CC(C)(C)OC(=O)N1CCN(C2(C#N)CCCCCC2)CC1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
USP2 O75604 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CTSK P43235 1/20 0.42
EPHX1 P07099 1/20 0.42
EPHX2 P34913 1/20 0.40
GPR119 Q8TDV5 2/20 0.38
CTSS P25774 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14306563 1.00 HPGD (0.43) HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL14314348 0.99 USP2 (0.44) HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL31180103 0.89 HPGD (0.47) HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL14314342 0.87 EPHX2 (0.42) HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL14314344 0.86 USP2 (0.41) HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL994040 0.86 USP2 (0.55) HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL13587115 0.84 USP2 (0.42) HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL14314343 0.84 HRH3 (0.40) HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL18406799 0.83 USP2 (0.50) HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL28835986 0.83 USP2 (0.43) HPGDMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4305026-B1 ANTI-INFLAMMATORY CARBOXAMIDE DERIVATIVES BIOMEDCODE HELLAS SA (GR) 2025-05-07 EP disclosed
US-20240308954-A1 ANTI-INFLAMMATORY CARBOXAMIDE DERIVATIVES BIOMEDCODE HELLAS SA (GR) 2024-09-19 US disclosed
EP-4305026-A1 ANTI-INFLAMMATORY CARBOXAMIDE DERIVATIVES Biomedcode Hellas SA (GR) 2024-01-17 EP disclosed
WO-2022189636-A1 ANTI-INFLAMMATORY CARBOXAMIDE DERIVATIVES BIOMEDCODE HELLAS SA (GR) 2022-09-15 WO disclosed
US-9133204-B2 5-membered heterocyclic amides and related compounds H. LUNDBECK A/S (DK) 2015-09-15 US disclosed
EP-2178865-B1 5-MEMBERED HETEROCYCLIC AMIDES AND RELATED COMPOUNDS LUNDBECK H AS (DK) 2015-08-19 EP disclosed
US-20150005293-A1 5-Membered Heterocyclic Amides And Related Compounds MINDIMMUNE THERAPEUTICS, INC. 2015-01-01 US disclosed
US-20100292236-A1 5-Membered Heterocyclic Amides And Related Compounds H. LUNDBECK A/S (DK) 2010-11-18 US disclosed
EP-2178865-A2 5-MEMBERED HETEROCYCLIC AMIDES AND RELATED COMPOUNDS Lundbeck, H., A/S (DK) 2010-04-28 EP disclosed
WO-2009012482-A2 5-MEMBERED HETEROCYCLIC AMIDES AND RELATED COMPOUNDS H.LUNDBECK A/S (DK) 2009-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150005293-A1 5-Membered Heterocyclic Amides And Related Compounds GPR35, HCAR2, HCAR1 HPGD 388/4885MEN1 4162/4885KMT2A 3781/4885
US-20100292236-A1 5-Membered Heterocyclic Amides And Related Compounds GPR35, HCAR2, HCAR1 HPGD 388/4885MEN1 4162/4885KMT2A 3781/4885
US-20240308954-A1 ANTI-INFLAMMATORY CARBOXAMIDE DERIVATIVES IL1B, IL1A, CASP1 HPGD 203/4885MEN1 4363/4885KMT2A 1654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.